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Kalle Gehring Selected Research

Spastic ataxia Charlevoix-Saguenay type

10/2015Structural studies of parkin and sacsin: Mitochondrial dynamics in neurodegenerative diseases.
1/2015High-Throughput Screening for Ligands of the HEPN Domain of Sacsin.
1/2012Mitochondrial dysfunction and Purkinje cell loss in autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS).
6/2011Structural basis of defects in the sacsin HEPN domain responsible for autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS).

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Kalle Gehring Research Topics

Disease

14Neoplasms (Cancer)
01/2021 - 02/2006
4Parkinson Disease (Parkinson's Disease)
07/2022 - 09/2014
4Neurodegenerative Diseases (Neurodegenerative Disease)
10/2015 - 06/2011
4Spastic ataxia Charlevoix-Saguenay type
10/2015 - 06/2011
2Neoplasm Metastasis (Metastasis)
01/2020 - 03/2004
2Obesity
01/2014 - 07/2010
1Spastic Ataxia
01/2019
1Ataxia (Dyssynergia)
01/2019
1Inborn Genetic Diseases (Disease, Hereditary)
12/2018
1Carcinogenesis
01/2017
1Tuberculosis (Tuberculoses)
03/2016
1Polyneuropathies (Polyneuropathy)
06/2015
1Type 2 Diabetes Mellitus (MODY)
07/2010
1Breast Neoplasms (Breast Cancer)
07/2010
1Metabolic Diseases (Metabolic Disease)
07/2010
1Dehydration (Water Stress)
04/2007
1Starvation
05/2004

Drug/Important Bio-Agent (IBA)

10Proteins (Proteins, Gene)FDA Link
01/2019 - 05/2004
6Phosphoric Monoester Hydrolases (Phosphatases)IBA
01/2021 - 03/2004
3Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
07/2022 - 03/2010
2UbiquitinIBA
01/2018 - 11/2014
1Phosphotransferases (Kinase)IBA
07/2022
1Dual-Specificity PhosphatasesIBA
05/2019
1Ligases (Synthetase)IBA
01/2018
1ZincIBA
03/2016
11,2- diarachidonoyl- glycero- 3- phosphoethanolamine (DAPE)IBA
03/2016
1His-His-His-His-His-His ((His)6)IBA
03/2016
1alpha-N-acetyl-D-glucosaminidase (alpha-N-acetylglucosaminidase)IBA
06/2015
16-pyruvoyltetrahydropterin synthase (PTPS)IBA
01/2014
1Protein Tyrosine PhosphatasesIBA
01/2014
1GD2 gangliosideIBA
01/2012
1GlycosphingolipidsIBA
01/2012
1NucleotidesIBA
07/2010
1EnzymesIBA
07/2010
1Nucleotide AptamersIBA
07/2010
1Non-Receptor Type 1 Protein Tyrosine PhosphataseIBA
07/2010
1Pharmaceutical PreparationsIBA
06/2010
1SolutionsIBA
06/2010
1Peptides (Polypeptides)IBA
03/2010
1Poly(A)-Binding Proteins (Poly(A)-Binding Protein)IBA
03/2010
14-azidobenzylcarazolol (pABC)IBA
03/2010
1positive allosteric modulator PAM-2IBA
04/2007
1Plant ProteinsIBA
04/2007
1RibonucleoproteinsIBA
02/2006
1major vault proteinIBA
02/2006
1GlycogenIBA
05/2004

Therapy/Procedure

5Therapeutics
07/2022 - 02/2006